Phospho-erk5
WebJun 23, 2024 · Except for ERK5, which contains a long carboxy (C)-terminal domain, the conventional MAPKs consist of a single kinase domain (KD) with short amino (N) and C terminals. ... their phospho-activating ... WebFeb 4, 2016 · The pre-B-cell receptor (pre-BCR) is an important checkpoint of B-cell development and is essential for a pre-B cell to traverse into an immature B cell. Here, we show that activation of myocyte enhancer factor 2 (Mef2) transcription factors (TFs) by the pre-BCR is necessary for initiating the subsequent genetic network.
Phospho-erk5
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WebApr 8, 2024 · For the Human Phospho‐Kinase Array (ref. ARY003B, R&D Systems), cell lysates of the ovarian cancer cell lines were hybridised to the array following provider's instructions for simultaneously detecting the relative levels of kinase phosphorylation sites. ... ERK5 autophosphorylation causes the appearance of a hyperphosphorylated form, … WebERK5 has a large C-terminal-half that contains a transcriptional activation domain. However, it has remained unclear how its transcriptional activation activity is regulated. ... Antibodies—Antibodies were purchased as follows: rabbit anti-phospho-ERK5 antibody from Cell Signaling; mouse anti-Myc (9E10) and mouse anti-HA (F-7) antibodies from ...
WebFeb 19, 2009 · The purpose of the present study was to investigate the role of myocyte enhancer binding factor 2C (MEF2C), a common substrate of p38 kinase and extracellular … WebPhospho-p44/42 MAPK (Erk1/2) (Thr202/Tyr204) Antibody detects endogenous levels of p44 and p42 MAP Kinase (Erk1 and Erk2) when phosphorylated either individually or dually at Thr202 and Tyr204 of Erk1 …
WebSep 29, 2009 · These are the extracellular regulated kinase (ERK)1/2 pathway, the ERK5 pathway, the p38 pathway and the c-Jun N-terminal kinase (JNK) pathway. In some forms of human breast cancer and in many experimental models of breast cancer progression, signalling through the ERK1/2 pathway, in particular, has been implicated as being …
WebPhospho-ERK5 (Thr218/Tyr220) Assay. Increased signal is observed with the titration of ERK5 positive cell lysate. Signal for negative lysate remains low throughout the titration. The p Phospho-ERK5 (Thr218/Tyr220) Assay provides a quantitative measure of the data obtained with the traditional Western blot.
Web上海士锋生物为您提供gp340抗体的参数及2024年最新报价，厂家专业的gp340抗体售后服务团队，是您值得信赖的合作伙伴 how to replace a toilet valveWebPhospho-ERK5 (Thr218/Tyr220) Assay. Increased signal is observed with the titration of ERK5 positive cell lysate. Signal for negative lysate remains low throughout the titration. … northarn siberian winds head preset femaleWebAnti-phospho-ERK5 (pThr218/pTyr220) antibody produced in rabbit (Anti-BMK1); affinity isolated antibody, buffered aqueous glycerol solution; Each vial contains enough material for 10 blots; Extracellular Signal-Regulated Kinases … north arrow clip artWebPhospho-ERK5 (Thr218, Tyr220) Antibody (44-612G) in WB Extracts prepared from HEK293 cells transiently transfected with plasmids expressing ERK5 kinase domain (ERK5kin) and constitutively activated MEK5D-D were resolved by SDS-PAGE on a 10% polyacrylamide gel and transferred to PVDF. north army civil warWebAnti-phospho-BMK1/Erk5 (Thr218/Tyr220) Antibody 07-507 Sigma-Aldrich Anti-phospho-BMK1/Erk5 (Thr218/Tyr220) Antibody Download Zoom This Anti-phospho-BMK1/Erk5 (Thr218/Tyr220) Antibody is validated for use in WB for the detection of phospho-BMK1/Erk5 (Thr218/Tyr220). how to replace a toto fill valveWebAug 29, 2008 · The role of the MAP kinase, extracellular signal-regulated kinase 5 (ERK5) remains unknown, however it is involved in cell differentiation and survival as highlighted by the embryonic lethality of the ERK5 knockout. ERK5 can be activated by growth factors and other extracellular signals. north arrow gcWebMar 27, 2024 · Moreover, potential specific changes in the expression of Epac1/2 proteins may occur in subcellular cardiac compartments that would require more precise investigations. 47, 48 Indeed, Epac1 was shown previously to mediate the pro-hypertrophic effects of β-AR stimulation 49 through either its recruitment to β 1-ARs via β-arrestin2 47 … north arrow for maps