WebUrokinase-type plasminogen activator (uPA) augments inflammation and tissue remodeling during lung injury and repair. The uPA expression in small airway epithelium of chronic obstructive pulmonary disease (COPD) increases. Epithelial–mesenchymal transition (EMT) is important in the small airway fibrosis of COPD. This study shows the uPA regulation in … WebUrokinase-type plasminogen activator (uPA) regulates angiogenesis and vascular permeability through proteolytic degradation of extracellular matrix and intracellular signaling initiated upon its binding to uPAR/CD87 and other cell surface receptors. Here, we describe an additional mechanism by which uPA regulates angiogenesis. Ex vivo VEGF-induced …
Yunika Upa - Google Scholar
WebDec 17, 2024 · The uPA protease inhibitor, WX-UK1, failed to inhibit the barrier breakdown in Caco-2 cells and in primary epithelial monolayers, indicating that the protease function … WebMar 31, 2024 · Urokinase plasminogen activator (uPA) is a crucial activator of the fibrinolytic system that modulates tissue remodeling, cancer progression, and inflammation. However, its role in membranous nephropathy (MN) remains unclear. To clarify this issue, an established mouse model mimicking human MN induced by cationic bovine serum … gmx analytics
Alexandra Leitão - Google Scholar
WebApr 11, 2024 · Google Scholar. Google Scholar is a search engine that specifically searches for scholarly literature. It finds peer-reviewed articles, preprints, technical reports, books, theses, abstracts, and even patents and court opinions, from multiple sources. These include academic publishers, university presses and repositories, professional societies ... WebJul 17, 2014 · Carnosic acid is a natural benzenediol abietane diterpene found in rosemary and exhibits anti-inflammatory, antioxidant, and anti-carcinogenic activities. In this study, we evaluated the effects of carnosic acid on the metastatic characteristics of B16F10 melanoma cells. When B16F10 cells were cultured in an in vitro Transwell system, carnosic acid … WebThe results showed that danshen increased the expressions of uPA, cyclin D1, E and ERK, JNK, and P38 MAP kinases via the FGF-2 signaling pathway in a dose-dependent manner. RSC96, Schwann cells were also administered with ... [Google Scholar] 5. Kuo W-W, Liu C-J, Chen L-M, et al. Cardiomyoblast apoptosis induced by insulin-like growth factor ... bombshells 45 north houston