Eif3b and bladder cancer
WebEIF3B. General description of the gene and the encoded protein (s) using information from HGNC and Ensembl, as well as predictions made by the Human Protein Atlas project. … WebTumor progression in response to EIF3B deficiency in vivo was investigated using the xenograft tumor model. Results: We found aberrantly high expression of EIF3B in pancreatic cancer, which associated with unfavorable prognosis. Knockdown of EIF3B greatly compromised cell viability and proliferation in both SW1990 and PANC-1 cells.
Eif3b and bladder cancer
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WebApr 19, 2024 · Diagnosing bladder cancer. Female cystoscopy. Male cystoscopy. Tests and procedures used to diagnose bladder cancer may include: Using a scope to … WebSep 1, 2024 · EIF3B was strongly expressed in malignant melanoma tissues and cells. A, B, The protein levels of EIF3B in 164 cases of malignant melanoma tumor tissues and 26 cases of paracarcinoma tissues were determined by immunohistochemical staining.
WebApr 10, 2013 · [8][9][10][11][12] EIF3b has been reported to be overexpressed in colon cancer cells and related to human bladder and prostate cancer prognosis 13, 14 … WebNov 13, 2024 · Regarding subunit b (eIF3b), its high expression has been observed in both human bladder and prostate tumors and correlates to cancer prognosis. Citation 68 In …
WebSep 3, 2024 · In addition, its expression related to human bladder and prostate cancer prognosis and was required for tumor growth . ... Wang H, Ru Y, Sanchez-Carbayo M, … WebApr 15, 2012 · Abstract. The initiation of translation in eukaryotes is promoted by multi-protein eukaryotic initiation factor complexes (eIFs). While several eIF subunits are overexpressed in cancer, very few have been conclusively implicated as drivers of human cancer phenotypes. Through a transcriptomic analysis of human bladder cancer our …
Web[4]. eIF3b is aberrantly expressed or activated in different types of human cancer. For example, it promoted prolif-eration and inhibited apoptosis in glioblastoma cells [5]. In addition, its expression related to human bladder and prostate cancer prognosis and was required for tumor growth [5]. In previous study, we have demonstrated
WebWe then showed that eIF3b depletion inhibited cell proliferation by compromising the cell cycle and inducing cell apoptosis. The G1/S arrest after eIF3b depletion has also been … martha paineWebApr 22, 2024 · Head and neck squamous cell carcinoma (HNSCC) is the sixth most common cancer type worldwide. Deregulation of mRNA translation is a frequent feature of … martha padgett des moines iowaWebJul 29, 2014 · Here, we investigated the impact of eIF3 expression on urinary bladder cancer (UBC) cell characteristics and UBC patient survival. Methods and results: eIF3a expression was reduced through... martha paiz john fogertyWebPurpose: Eph receptors are differentially expressed in numerous malignant tumors. This study intended to analyze the roles of EphB receptors (EphB2, B3, and B4) in urinary … martha paiz childrenWebEIF3B causes malignant transformation of immortal fibro-blast cells(NIH3T3).14 Moreover, highexpression of EIF3B was observed in several types of cancer and is associated with poor prognosis,12 such as clear cell renal cell carcinoma,15 esophageal squamous cell carcinoma,16 and bladder cancer.17 However, little is known about the rele-vance of ... martha page burkholder md tucsonWebFeb 22, 2024 · Wang et al. proved that EIF3B is upregulated in prostate and bladder cancer tissues and that it promotes bladder and prostate cancer growth and lung … martha paiz fogertyWebApr 10, 2013 · Depletion of eIF3b inhibits bladder cancer cell growth by inhibition of G1/S transition of the cell cycle (A) eIF3b was depleted by eIF3b siRNAs (oligos eIF3b-3 and eIF3b-4) in UMUC3 and Lul2 human bladder cancer cells. Cell growth was evaluated over five days by the alamarBlue assay. Data shown is the mean ± S.D. of fluorescence … martha paiz\u0027s daughter lyndsay fogerty